I joined the Regot lab as a master’s student in September 2023. In my free time, I enjoy playing squash, going on hikes, and keeping different kinds of invertebrate pets. My current research focuses on how ERK and MAPK signaling in general regulate cell cycle and cytoskeletal components. The link between ERK signaling, cell cycle,[...]

Multicellular organisms rely on the coordinated function of cells and tissues to support homeostasis. This cooperation begins very early in mammalian development, when embryos consist of single-digit cell numbers and functionally specialized groups of cells are formed by the time the embryo is a few hundred cells. Noise in gene expression generates early cellular heterogeneity[...]

What is life? To the casual observer, living things are easily distinguished from inanimate –they are entities that reproduce, grow, and adapt. But how do these processes occur? If we could fully understand them, would we control life and become masters of our own fates? Organisms exist through interactions with the very inorganic objects they[...]

Undergraduate researcher majoring in molecular and cellular biology at Johns Hopkins University

I am an undergraduate student working on a few projects around the lab! I am currently investigating ERK pathway dynamics using fluorescent biosensors in regards to how elements of the signaling cascade interact to generate pulses of activity. I am also involved in the lab’s work with macromolecular crowding and live cell screening of inhibitor[...]

My research focuses on understanding how antigen discrimination allows T cells to avert autoimmunity while still mounting potent responses against infected and transformed cells. In order to achieve this, T cells rely on a network of intricately connected and multilayered signaling pathways. Though the main players have been well characterized, the temporal dynamics regulating the[...]

Some cells in our body receive constant growth signals, such as in the intestine or the skin. However, they also face stresses such as DNA and RNA damage from UV light or inflammatory signals from neighboring cells. I am interested in studying how these pro- and anti-growth signals are integrated by cells, and how competing[...]

The classic network of mitogen-activated protein kinases (MAPKs) is highly interconnected and controls a diverse array of biological processes. In multicellular eukaryotes, the MAPKs ERK, JNK, and p38 control opposing cell behaviors but are often activated simultaneously, raising questions about how input-output specificity is achieved. Here, we use multiplexed MAPK activity biosensors to investigate how[...]

We are each a wonder. How do trillions of individual units, our cells, function in harmony to build and maintain a functional organism over the course of a life? Cells are fine-tuned to respond to environmental cues to grow and divide, differentiate, navigate their surroundings, produce and consume resources, and countless other behaviors. Somehow, our[...]