The integral of ERK activity, irrespective of its dynamics, controls mESC exit from pluripotency. A nice optogenetics based study also revealing interesting memory effect (with decay ~ 2 X pulse duration). https://t.co/7nRtyDFxH1 pic.twitter.com/XpALgrdfyA

— Levayerlab (@LevayerR) June 20, 2023